Cefmetazole












































































Cefmetazole
Cefmetazole.svg
Clinical data

AHFS/Drugs.com
 International Drug Names
MedlinePlus a601206
ATC code

  • J01DC09 (WHO)
Identifiers
CAS Number

  • 56796-20-4 ☑Y

PubChem CID
  • 42008
DrugBank

  • DB00274 ☑Y
ChemSpider

  • 38311 ☑Y
UNII
  • 3J962UJT8H
KEGG

  • D00910 ☑Y
ChEBI

  • CHEBI:3489 ☑Y
ChEMBL

  • ChEMBL1201195 ☒N
ECHA InfoCard
100.054.877 Edit this at Wikidata
Chemical and physical data
Formula
C15H17N7O5S3
Molar mass 471.538 g/mol
3D model (JSmol)
  • Interactive image

.mw-parser-output .nobold{font-weight:normal}
 ☒N☑Y (what is this?)
  (verify)

Cefmetazole is a cephamycin antibiotic, usually grouped with the second-generation cephalosporins.



Adverse effects


The chemical structure of cefmetazole, like that of several other cephalosporins, contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain. As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram, due to inhibition of aldehyde dehydrogenase.[1]



Spectrum of bacterial susceptibility


Cefmetazole is a broad-spectrum cephalosporin antimicrobial and has been effective in treating bacteria responsible for causing urinary tract and skin infections. The following represents MIC susceptibility data for a few medically significant microorganisms.




  • Bacteroides fragilis: 0.06 - >256 µg/ml


  • Clostridium difficile: 8 - >128 µg/ml


  • Staphylococcus aureus: 0.5 - 256 µg/ml (includes MRSA)


[2]



References





  1. ^ Stork CM (2006). "Antibiotics, antifungals, and antivirals". In Nelson LH, Flomenbaum N, Goldfrank LR, Hoffman RL, Howland MD, Lewin NA. Goldfrank's toxicologic emergencies. New York: McGraw-Hill. p. 847. ISBN 0-07-143763-0. Retrieved 2009-07-03..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output q{quotes:"""""""'""'"}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-limited a,.mw-parser-output .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}


  2. ^ http://www.toku-e.com/Assets/MIC/Cefmetazole%20free%20acid.pdf










-

這個網誌中的熱門文章

Xamarin.form Move up view when keyboard appear

圖片
.everyoneloves__top-leaderboard:empty,.everyoneloves__mid-leaderboard:empty,.everyoneloves__bot-mid-leaderboard:empty{ height:90px;width:728px;box-sizing:border-box; } 0 I'm trying to build a Chat app UI, the idea of the Layout was pretty simple: When the input bar is focused, keyboard show up and "push" up the chat bar, as it's a grid, the ListView will resize to fit the screen: I update the input bar's margin to "push" it up: NSValue result = (NSValue)args.Notification.UserInfo.ObjectForKey(new NSString(UIKeyboard.FrameEndUserInfoKey)); CGSize keyboardSize = result.RectangleFValue.Size; if (Element != null){ Element.Margin = new Thickness(0, 0, 0,keyboardSize.Height); //push the entry up to keyboard height when keyboard is activated } And this is ...
閱讀完整內容

Post-Redirect-Get with Spring WebFlux and Thymeleaf

圖片
.everyoneloves__top-leaderboard:empty,.everyoneloves__mid-leaderboard:empty,.everyoneloves__bot-mid-leaderboard:empty{ height:90px;width:728px;box-sizing:border-box; } 2 Can someone explain to me how to implement the post-redirect-get pattern in Spring WebFlux and Thymeleaf? What subscribes on the database save method? @GetMapping("/register") public String showRegisterForm(Model model) { model.addAttribute("user", new User()); return "register"; } @PostMapping public String processRegisterForm(@Valid User user, BindingResult bindingResult) { if (bindingResult.hasErrors()) { return "register"; } else { userRepository.save(user); //what subscribes on this? //how to redirect on e.g. "/login"? ...
閱讀完整內容

Anylogic : not able to use stopDelay()

圖片
-2 I am building a railway station model. I want a train to depart when I click a button. I want to call stopDelay() for that but I am not sure how to do that and from which place. anylogic share | improve this question asked Nov 23 '18 at 10:12 Anupam Singh Anupam Singh 1 Hi Anupam, welcome to SOF. Please check how to ask good questions, see link below. Your question is...
閱讀完整內容